Drug interactions
Citalopram + Glipizide-metformin
Severity: Minor
Citalopram and Glipizide-metformin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
SSRIs may modestly change glycemic control in people with diabetes, and hypoglycemia has been reported with sulfonylureas in some cases. The effect is inconsistent and usually small.
What this interaction means in plain words
Citalopram and Glipizide-metformin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Citalopram belongs to Central Nervous System; Glipizide-metformin belongs to Endocrine.
Why it happens
The mechanism is not well established; SSRIs may improve insulin sensitivity or alter glucose counter-regulation.
What to do
Check blood glucose more often when citalopram is started or stopped and adjust antidiabetic doses only if readings change.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Glipizide-metformin
Other interactions of Citalopram
- Cisapride + Citalopram Contraindicated
- Citalopram + Dronedarone Contraindicated
- Citalopram + Escitalopram Contraindicated
- Citalopram + Isocarboxazid Contraindicated
- Citalopram + Methylene blue Contraindicated
- Citalopram + Phenelzine Contraindicated
Frequently asked questions
Can I take Citalopram with Glipizide-metformin?
MediHelp rates the interaction as minor. Citalopram and Glipizide-metformin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. SSRIs may modestly change glycemic control in people with diabetes, and hypoglycemia has been reported with sulfonylureas in some cases. The effect is inconsistent and usually small.
How serious is the interaction between Citalopram and Glipizide-metformin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check blood glucose more often when citalopram is started or stopped and adjust antidiabetic doses only if readings change.
What other medicines interact with Glipizide-metformin?
MediHelp also lists interactions of Glipizide-metformin with, for example, Contrast media, Diatrizoate meglumine / diatrizoate, Diatrizoate. The full list is on the Glipizide-metformin page.
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