Drug interactions
Citalopram + Metformin-repaglinide
Severity: Minor
Citalopram and Metformin-repaglinide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
SSRIs may improve insulin sensitivity or alter glucose regulation, occasionally causing hypoglycemia in patients on antidiabetic agents. The effect is variable and usually mild.
What this interaction means in plain words
Citalopram and Metformin-repaglinide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Citalopram belongs to Central Nervous System; Metformin-repaglinide belongs to Endocrine.
Why it happens
Additive glucose lowering through serotonergic effects on insulin sensitivity; mechanism not fully established.
What to do
Monitor blood glucose when citalopram is started or stopped, and adjust antidiabetic doses if needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Metformin-repaglinide
Other interactions of Citalopram
- Cisapride + Citalopram Contraindicated
- Citalopram + Dronedarone Contraindicated
- Citalopram + Escitalopram Contraindicated
- Citalopram + Isocarboxazid Contraindicated
- Citalopram + Methylene blue Contraindicated
- Citalopram + Phenelzine Contraindicated
Frequently asked questions
Can I take Citalopram with Metformin-repaglinide?
MediHelp rates the interaction as minor. Citalopram and Metformin-repaglinide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. SSRIs may improve insulin sensitivity or alter glucose regulation, occasionally causing hypoglycemia in patients on antidiabetic agents. The effect is variable and usually mild.
How serious is the interaction between Citalopram and Metformin-repaglinide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when citalopram is started or stopped, and adjust antidiabetic doses if needed.
What other medicines interact with Metformin-repaglinide?
MediHelp also lists interactions of Metformin-repaglinide with, for example, Gemfibrozil, Apalutamide, Clarithromycin. The full list is on the Metformin-repaglinide page.
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