Drug interactions
Citalopram + Timolol
Severity: Minor
Citalopram and Timolol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Citalopram is a weak CYP2D6 inhibitor and may slightly raise timolol levels, which could increase bradycardia or hypotension. The effect is generally small.
What this interaction means in plain words
Citalopram and Timolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Citalopram belongs to Central Nervous System; Timolol belongs to Cardiovascular.
Why it happens
Weak inhibition of CYP2D6 by citalopram reduces timolol metabolism.
What to do
No routine dose change is needed; check heart rate and blood pressure when citalopram is started or the dose changed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Timolol
- Acebutolol + Timolol Major
- Aldesleukin + Timolol Major
- Amifostine + Timolol Major
- Amiodarone + Timolol Major
- Arformoterol + Timolol Major
- Atenolol-chlorthalidone + Timolol Major
Other interactions of Citalopram
- Cisapride + Citalopram Contraindicated
- Citalopram + Dronedarone Contraindicated
- Citalopram + Escitalopram Contraindicated
- Citalopram + Isocarboxazid Contraindicated
- Citalopram + Methylene blue Contraindicated
- Citalopram + Phenelzine Contraindicated
Frequently asked questions
Can I take Citalopram with Timolol?
MediHelp rates the interaction as minor. Citalopram and Timolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Citalopram is a weak CYP2D6 inhibitor and may slightly raise timolol levels, which could increase bradycardia or hypotension. The effect is generally small.
How serious is the interaction between Citalopram and Timolol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine dose change is needed; check heart rate and blood pressure when citalopram is started or the dose changed.
What other medicines interact with Timolol?
MediHelp also lists interactions of Timolol with, for example, Acebutolol, Aldesleukin, Amifostine. The full list is on the Timolol page.
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