Drug interactions
Codeine + Levosalbutamol
Severity: Minor
Codeine and Levosalbutamol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Codeine produces sedation and respiratory depression, while levosalbutamol is a bronchodilator with mild stimulant effects. No clinically important interaction is established, although opioids may worsen breathing in patients with severe airway disease.
What this interaction means in plain words
Codeine and Levosalbutamol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Codeine belongs to Musculoskeletal; Levosalbutamol belongs to Respiratory.
Why it happens
No established pharmacokinetic or pharmacodynamic interaction; any opposing CNS effect is theoretical.
What to do
No dose adjustment is needed. Monitor respiratory status in patients with asthma or COPD receiving opioids.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Levosalbutamol
Other interactions of Codeine
- Alvimopan + Codeine Contraindicated
- Codeine + Isocarboxazid Contraindicated
- Codeine + Olanzapine / samidorphan Contraindicated
- Codeine + Phenelzine Contraindicated
- Codeine + Tranylcypromine Contraindicated
- Alfentanil + Codeine Major
Frequently asked questions
Can I take Codeine with Levosalbutamol?
MediHelp rates the interaction as minor. Codeine and Levosalbutamol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Codeine produces sedation and respiratory depression, while levosalbutamol is a bronchodilator with mild stimulant effects. No clinically important interaction is established, although opioids may worsen breathing in patients with severe airway disease.
How serious is the interaction between Codeine and Levosalbutamol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose adjustment is needed. Monitor respiratory status in patients with asthma or COPD receiving opioids.
What other medicines interact with Levosalbutamol?
MediHelp also lists interactions of Levosalbutamol with, for example, Amisulpride, Carvedilol, Fexinidazole. The full list is on the Levosalbutamol page.
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