Drug interactions
Conivaptan + Desogestrel-ethinyl estradiol
Severity: Minor
Conivaptan and Desogestrel-ethinyl estradiol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Conivaptan is a CYP3A4 inhibitor and may increase ethinyl estradiol and progestin concentrations. Conivaptan is used only short term as an IV infusion, so the effect is typically limited.
What this interaction means in plain words
Conivaptan and Desogestrel-ethinyl estradiol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Inhibition of CYP3A4 by conivaptan decreases metabolism of ethinyl estradiol.
What to do
No routine change is needed for the short infusion; monitor for estrogenic adverse effects such as nausea or breast tenderness.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Desogestrel-ethinyl estradiol
- Desogestrel-ethinyl estradiol + Fezolinetant Contraindicated
- Aminocaproic acid + Desogestrel-ethinyl estradiol Major
- Amobarbital + Desogestrel-ethinyl estradiol Major
- Anastrozole + Desogestrel-ethinyl estradiol Major
- Apalutamide + Desogestrel-ethinyl estradiol Major
- Atazanavir + Desogestrel-ethinyl estradiol Major
Frequently asked questions
Can I take Conivaptan with Desogestrel-ethinyl estradiol?
MediHelp rates the interaction as minor. Conivaptan and Desogestrel-ethinyl estradiol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Conivaptan is a CYP3A4 inhibitor and may increase ethinyl estradiol and progestin concentrations. Conivaptan is used only short term as an IV infusion, so the effect is typically limited.
How serious is the interaction between Conivaptan and Desogestrel-ethinyl estradiol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine change is needed for the short infusion; monitor for estrogenic adverse effects such as nausea or breast tenderness.
What other medicines interact with Desogestrel-ethinyl estradiol?
MediHelp also lists interactions of Desogestrel-ethinyl estradiol with, for example, Fezolinetant, Aminocaproic acid, Amobarbital. The full list is on the Desogestrel-ethinyl estradiol page.
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