Drug interactions
Conjugated estrogens + Ropinirole
Severity: Minor
Conjugated estrogens and Ropinirole: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Estrogens may raise ropinirole exposure, as seen with ethinylestradiol-containing therapy in postmenopausal women. Ropinirole-related effects such as nausea, dizziness, somnolence or orthostatic hypotension could be more pronounced.
What this interaction means in plain words
Conjugated estrogens and Ropinirole have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Probable reduced CYP1A2-mediated clearance of ropinirole by estrogens, although the mechanism is not firmly established.
What to do
No routine change is needed. If dopaminergic adverse effects emerge after starting or stopping estrogen, adjust the ropinirole dose accordingly.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Conjugated estrogens and Ropinirole, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Ropinirole
- Amisulpride + Ropinirole Contraindicated
- Chlorpromazine + Ropinirole Major
- Droperidol + Ropinirole Major
- Fluphenazine + Ropinirole Major
- Fluvoxamine + Ropinirole Major
- Haloperidol + Ropinirole Major
Frequently asked questions
Can I take Conjugated estrogens with Ropinirole?
MediHelp rates the interaction as minor. Conjugated estrogens and Ropinirole have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Estrogens may raise ropinirole exposure, as seen with ethinylestradiol-containing therapy in postmenopausal women. Ropinirole-related effects such as nausea, dizziness, somnolence or orthostatic hypotension could be more pronounced.
How serious is the interaction between Conjugated estrogens and Ropinirole?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine change is needed. If dopaminergic adverse effects emerge after starting or stopping estrogen, adjust the ropinirole dose accordingly.
What other medicines interact with Ropinirole?
MediHelp also lists interactions of Ropinirole with, for example, Amisulpride, Chlorpromazine, Droperidol. The full list is on the Ropinirole page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
