Drug interactions
Contrast media + Foscarnet
Severity: Moderate
Contrast media and Foscarnet: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Foscarnet is a well-known cause of renal impairment, and iodinated contrast can cause contrast-associated kidney injury. Using them together increases the risk of acute kidney injury.
What this interaction means in plain words
Contrast media and Foscarnet can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive nephrotoxicity.
What to do
Ensure adequate hydration and monitor serum creatinine before and after contrast. Use the lowest effective contrast dose and consider delaying non-urgent imaging.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Foscarnet
- Cidofovir + Foscarnet Contraindicated
- Foscarnet + Pimozide Contraindicated
- Foscarnet + Thioridazine Contraindicated
- Foscarnet + Vandetanib Contraindicated
- Adagrasib + Foscarnet Major
- Adefovir + Foscarnet Major
Frequently asked questions
Can I take Contrast media with Foscarnet?
MediHelp rates the interaction as moderate. Contrast media and Foscarnet can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Foscarnet is a well-known cause of renal impairment, and iodinated contrast can cause contrast-associated kidney injury. Using them together increases the risk of acute kidney injury.
How serious is the interaction between Contrast media and Foscarnet?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Ensure adequate hydration and monitor serum creatinine before and after contrast. Use the lowest effective contrast dose and consider delaying non-urgent imaging.
What other medicines interact with Foscarnet?
MediHelp also lists interactions of Foscarnet with, for example, Cidofovir, Pimozide, Thioridazine. The full list is on the Foscarnet page.
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