Drug interactions
Cortisone + Erlotinib
Severity: Minor
Cortisone and Erlotinib: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Cortisone is a weak CYP3A4 inducer at most, and any reduction in erlotinib exposure is expected to be small. Clinical significance is unlikely to be meaningful at usual replacement or short-course doses.
What this interaction means in plain words
Cortisone and Erlotinib have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible weak induction of CYP3A4 by corticosteroids may slightly increase erlotinib clearance.
What to do
No dose change is normally needed. Be aware of the possibility if erlotinib response appears reduced.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Erlotinib
- Amobarbital + Erlotinib Major
- Apalutamide + Erlotinib Major
- Carbamazepine + Erlotinib Major
- Cobicistat + Erlotinib Major
- Darunavir + Erlotinib Major
- Dexlansoprazole + Erlotinib Major
Frequently asked questions
Can I take Cortisone with Erlotinib?
MediHelp rates the interaction as minor. Cortisone and Erlotinib have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Cortisone is a weak CYP3A4 inducer at most, and any reduction in erlotinib exposure is expected to be small. Clinical significance is unlikely to be meaningful at usual replacement or short-course doses.
How serious is the interaction between Cortisone and Erlotinib?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change is normally needed. Be aware of the possibility if erlotinib response appears reduced.
What other medicines interact with Erlotinib?
MediHelp also lists interactions of Erlotinib with, for example, Amobarbital, Apalutamide, Carbamazepine. The full list is on the Erlotinib page.
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