Drug interactions
Cortisone + Fesoterodine
Severity: Minor
Cortisone and Fesoterodine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Cortisone is a weak CYP3A4 inducer at most, so any reduction in the active metabolite of fesoterodine is expected to be small. A clinically meaningful loss of bladder antimuscarinic effect is unlikely.
What this interaction means in plain words
Cortisone and Fesoterodine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible weak induction of CYP3A4, which contributes to clearance of the active metabolite 5-hydroxymethyl tolterodine.
What to do
No dose change is needed; reassess urinary symptom control if the response to fesoterodine declines during prolonged high-dose corticosteroid therapy.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Fesoterodine
Frequently asked questions
Can I take Cortisone with Fesoterodine?
MediHelp rates the interaction as minor. Cortisone and Fesoterodine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Cortisone is a weak CYP3A4 inducer at most, so any reduction in the active metabolite of fesoterodine is expected to be small. A clinically meaningful loss of bladder antimuscarinic effect is unlikely.
How serious is the interaction between Cortisone and Fesoterodine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change is needed; reassess urinary symptom control if the response to fesoterodine declines during prolonged high-dose corticosteroid therapy.
What other medicines interact with Fesoterodine?
MediHelp also lists interactions of Fesoterodine with, for example, Bethanechol, Clozapine, Levoketoconazole. The full list is on the Fesoterodine page.
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