Drug interactions
Cortisone + Quinine
Severity: Minor
Cortisone and Quinine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Corticosteroids may weakly induce CYP3A4 and slightly lower quinine levels. The clinical significance is likely small.
What this interaction means in plain words
Cortisone and Quinine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Weak CYP3A4 induction by cortisone.
What to do
No routine change is needed; monitor treatment response if quinine is used for malaria during prolonged steroid therapy.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Quinine
- Arsenic trioxide + Quinine Contraindicated
- Dofetilide + Quinine Contraindicated
- Dronedarone + Quinine Contraindicated
- Ibutilide + Quinine Contraindicated
- Mefloquine + Quinine Contraindicated
- Nilotinib + Quinine Contraindicated
Frequently asked questions
Can I take Cortisone with Quinine?
MediHelp rates the interaction as minor. Cortisone and Quinine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Corticosteroids may weakly induce CYP3A4 and slightly lower quinine levels. The clinical significance is likely small.
How serious is the interaction between Cortisone and Quinine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine change is needed; monitor treatment response if quinine is used for malaria during prolonged steroid therapy.
What other medicines interact with Quinine?
MediHelp also lists interactions of Quinine with, for example, Arsenic trioxide, Dofetilide, Dronedarone. The full list is on the Quinine page.
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