Drug interactions
Cosyntropin + Eprosartan-hydrochlorothiazide
Severity: Minor
Cosyntropin and Eprosartan-hydrochlorothiazide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Cosyntropin is a single-dose diagnostic agent that briefly stimulates adrenal cortisol and some mineralocorticoid release. Any added electrolyte loss with hydrochlorothiazide would be small and short-lived.
What this interaction means in plain words
Cosyntropin and Eprosartan-hydrochlorothiazide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Cosyntropin belongs to Musculoskeletal; Eprosartan-hydrochlorothiazide belongs to Cardiovascular.
Why it happens
Transient adrenal stimulation may modestly add to thiazide-related potassium loss; the effect is not well established.
What to do
No routine action is needed for a single diagnostic test; check potassium if the patient is symptomatic or has other risk factors for hypokalemia.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Eprosartan-hydrochlorothiazide
- Aliskiren + Eprosartan-hydrochlorothiazide Contraindicated
- Dofetilide + Eprosartan-hydrochlorothiazide Contraindicated
- Eprosartan-hydrochlorothiazide + Sparsentan Contraindicated
- Aceclofenac + Eprosartan-hydrochlorothiazide Major
- Aldesleukin + Eprosartan-hydrochlorothiazide Major
- Amifostine + Eprosartan-hydrochlorothiazide Major
Other interactions of Cosyntropin
Frequently asked questions
Can I take Cosyntropin with Eprosartan-hydrochlorothiazide?
MediHelp rates the interaction as minor. Cosyntropin and Eprosartan-hydrochlorothiazide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Cosyntropin is a single-dose diagnostic agent that briefly stimulates adrenal cortisol and some mineralocorticoid release. Any added electrolyte loss with hydrochlorothiazide would be small and short-lived.
How serious is the interaction between Cosyntropin and Eprosartan-hydrochlorothiazide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action is needed for a single diagnostic test; check potassium if the patient is symptomatic or has other risk factors for hypokalemia.
What other medicines interact with Eprosartan-hydrochlorothiazide?
MediHelp also lists interactions of Eprosartan-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Eprosartan-hydrochlorothiazide page.
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