Drug interactions
Cyclopenthiazide + Eprosartan
Severity: Minor
Cyclopenthiazide and Eprosartan: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Cyclopenthiazide with eprosartan gives additive blood pressure reduction. Volume depletion, hypotension and renal function change can occur initially, while potassium loss from the diuretic is partly offset.
What this interaction means in plain words
Cyclopenthiazide and Eprosartan have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Additive blood pressure lowering from diuresis and angiotensin receptor blockade, with opposing potassium effects.
What to do
Monitor blood pressure, electrolytes and creatinine after initiation or dose changes.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Eprosartan
- Aliskiren + Eprosartan Contraindicated
- Eprosartan + Sparsentan Contraindicated
- Amifostine + Eprosartan Major
- Amiloride + Eprosartan Major
- Amlodipine-benazepril + Eprosartan Major
- Amlodipine-hydrochlorothiazide-valsartan + Eprosartan Major
Frequently asked questions
Can I take Cyclopenthiazide with Eprosartan?
MediHelp rates the interaction as minor. Cyclopenthiazide and Eprosartan have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Cyclopenthiazide with eprosartan gives additive blood pressure reduction. Volume depletion, hypotension and renal function change can occur initially, while potassium loss from the diuretic is partly offset.
How serious is the interaction between Cyclopenthiazide and Eprosartan?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure, electrolytes and creatinine after initiation or dose changes.
What other medicines interact with Eprosartan?
MediHelp also lists interactions of Eprosartan with, for example, Aliskiren, Sparsentan, Amifostine. The full list is on the Eprosartan page.
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