Drug interactions
Cyclosporin + Haemophilus influenzae type b vaccine
Severity: Moderate
Cyclosporin and Haemophilus influenzae type b vaccine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Cyclosporine suppresses T-cell function and may blunt the antibody response to this inactivated conjugate vaccine. Patients may remain inadequately protected.
What this interaction means in plain words
Cyclosporin and Haemophilus influenzae type b vaccine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Immunosuppression by calcineurin inhibition impairs vaccine-induced immune response.
What to do
Vaccinate at least 2 weeks before starting cyclosporine when possible. If given during therapy, consider checking antibody response or revaccinating after immune recovery.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Cyclosporin and Haemophilus influenzae type b vaccine, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Cyclosporin
- Adenovirus types 4 and 7 live + Cyclosporin Contraindicated
- Aliskiren + Cyclosporin Contraindicated
- Bcg vaccine live + Cyclosporin Contraindicated
- Bosentan + Cyclosporin Contraindicated
- Cidofovir + Cyclosporin Contraindicated
- Cyclosporin + Dengue vaccine Contraindicated
Frequently asked questions
Can I take Cyclosporin with Haemophilus influenzae type b vaccine?
MediHelp rates the interaction as moderate. Cyclosporin and Haemophilus influenzae type b vaccine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Cyclosporine suppresses T-cell function and may blunt the antibody response to this inactivated conjugate vaccine. Patients may remain inadequately protected.
How serious is the interaction between Cyclosporin and Haemophilus influenzae type b vaccine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Vaccinate at least 2 weeks before starting cyclosporine when possible. If given during therapy, consider checking antibody response or revaccinating after immune recovery.
What other medicines interact with Cyclosporin?
MediHelp also lists interactions of Cyclosporin with, for example, Adenovirus types 4 and 7 live, Aliskiren, Bcg vaccine live. The full list is on the Cyclosporin page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
