Drug interactions
Cyclosporin + Rabies vaccine chick embryo cell derived
Severity: Moderate
Cyclosporin and Rabies vaccine chick embryo cell derived: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Cyclosporine can reduce the antibody response to this inactivated rabies vaccine. Protection may be incomplete in immunosuppressed patients.
What this interaction means in plain words
Cyclosporin and Rabies vaccine chick embryo cell derived can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Calcineurin inhibition impairs T-cell dependent immune responses needed for vaccine immunogenicity.
What to do
Vaccinate before immunosuppression when possible; otherwise measure rabies neutralizing antibody titers after the series and give additional doses if inadequate.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Cyclosporin
- Adenovirus types 4 and 7 live + Cyclosporin Contraindicated
- Aliskiren + Cyclosporin Contraindicated
- Bcg vaccine live + Cyclosporin Contraindicated
- Bosentan + Cyclosporin Contraindicated
- Cidofovir + Cyclosporin Contraindicated
- Cyclosporin + Dengue vaccine Contraindicated
Frequently asked questions
Can I take Cyclosporin with Rabies vaccine chick embryo cell derived?
MediHelp rates the interaction as moderate. Cyclosporin and Rabies vaccine chick embryo cell derived can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Cyclosporine can reduce the antibody response to this inactivated rabies vaccine. Protection may be incomplete in immunosuppressed patients.
How serious is the interaction between Cyclosporin and Rabies vaccine chick embryo cell derived?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Vaccinate before immunosuppression when possible; otherwise measure rabies neutralizing antibody titers after the series and give additional doses if inadequate.
What other medicines interact with Cyclosporin?
MediHelp also lists interactions of Cyclosporin with, for example, Adenovirus types 4 and 7 live, Aliskiren, Bcg vaccine live. The full list is on the Cyclosporin page.
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