Drug interactions
Cyclosporin + Triamcinolone acetonide extended-release injectable
Severity: Minor
Cyclosporin and Triamcinolone acetonide extended-release injectable: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Cyclosporine may raise corticosteroid exposure, and corticosteroids may alter cyclosporine levels. With intra-articular extended-release triamcinolone, systemic effects are usually small but possible.
What this interaction means in plain words
Cyclosporin and Triamcinolone acetonide extended-release injectable have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Cyclosporine inhibits CYP3A4 metabolism of triamcinolone; corticosteroids may modulate cyclosporine clearance.
What to do
No routine change needed. Monitor for steroid excess such as Cushingoid features and check cyclosporine levels if repeated injections are given.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Cyclosporin
- Adenovirus types 4 and 7 live + Cyclosporin Contraindicated
- Aliskiren + Cyclosporin Contraindicated
- Bcg vaccine live + Cyclosporin Contraindicated
- Bosentan + Cyclosporin Contraindicated
- Cidofovir + Cyclosporin Contraindicated
- Cyclosporin + Dengue vaccine Contraindicated
Frequently asked questions
Can I take Cyclosporin with Triamcinolone acetonide extended-release injectable?
MediHelp rates the interaction as minor. Cyclosporin and Triamcinolone acetonide extended-release injectable have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Cyclosporine may raise corticosteroid exposure, and corticosteroids may alter cyclosporine levels. With intra-articular extended-release triamcinolone, systemic effects are usually small but possible.
How serious is the interaction between Cyclosporin and Triamcinolone acetonide extended-release injectable?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine change needed. Monitor for steroid excess such as Cushingoid features and check cyclosporine levels if repeated injections are given.
What other medicines interact with Cyclosporin?
MediHelp also lists interactions of Cyclosporin with, for example, Adenovirus types 4 and 7 live, Aliskiren, Bcg vaccine live. The full list is on the Cyclosporin page.
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