Drug interactions
Cyclosporin + Triamcinolone acetonide injectable
Severity: Moderate
Cyclosporin and Triamcinolone acetonide injectable: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Cyclosporine may raise triamcinolone exposure, and corticosteroids may change cyclosporine concentrations. Systemic corticosteroid toxicity or altered immunosuppression may follow.
What this interaction means in plain words
Cyclosporin and Triamcinolone acetonide injectable can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Cyclosporine inhibits CYP3A4 metabolism of triamcinolone; corticosteroids may modulate cyclosporine clearance.
What to do
Monitor for corticosteroid adverse effects such as adrenal suppression and hyperglycemia. Check cyclosporine trough levels if systemic doses or repeated injections are used.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Cyclosporin
- Adenovirus types 4 and 7 live + Cyclosporin Contraindicated
- Aliskiren + Cyclosporin Contraindicated
- Bcg vaccine live + Cyclosporin Contraindicated
- Bosentan + Cyclosporin Contraindicated
- Cidofovir + Cyclosporin Contraindicated
- Cyclosporin + Dengue vaccine Contraindicated
Frequently asked questions
Can I take Cyclosporin with Triamcinolone acetonide injectable?
MediHelp rates the interaction as moderate. Cyclosporin and Triamcinolone acetonide injectable can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Cyclosporine may raise triamcinolone exposure, and corticosteroids may change cyclosporine concentrations. Systemic corticosteroid toxicity or altered immunosuppression may follow.
How serious is the interaction between Cyclosporin and Triamcinolone acetonide injectable?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for corticosteroid adverse effects such as adrenal suppression and hyperglycemia. Check cyclosporine trough levels if systemic doses or repeated injections are used.
What other medicines interact with Cyclosporin?
MediHelp also lists interactions of Cyclosporin with, for example, Adenovirus types 4 and 7 live, Aliskiren, Bcg vaccine live. The full list is on the Cyclosporin page.
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