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Drug interactions

Cyproheptadine + Gotu kola

Severity: Minor

Cyproheptadine and Gotu kola: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Gotu kola has traditionally been reported to have sedative properties and may add to the drowsiness caused by cyproheptadine. The evidence is limited and largely theoretical.

What this interaction means in plain words

Cyproheptadine and Gotu kola have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

Possible additive sedation; the mechanism of gotu kola's sedative effect is not well established.

What to do

Advise patients about possible increased drowsiness and caution when driving. Stop the herbal product if excess sedation occurs.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Cyproheptadine with Gotu kola?

MediHelp rates the interaction as minor. Cyproheptadine and Gotu kola have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Gotu kola has traditionally been reported to have sedative properties and may add to the drowsiness caused by cyproheptadine. The evidence is limited and largely theoretical.

How serious is the interaction between Cyproheptadine and Gotu kola?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients about possible increased drowsiness and caution when driving. Stop the herbal product if excess sedation occurs.

What other medicines interact with Cyproheptadine?

MediHelp also lists interactions of Cyproheptadine with, for example, Isocarboxazid, Phenelzine, Tranylcypromine. The full list is on the Cyproheptadine page.

Full monographs, dosing and an interaction checker in the MediHelp app

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