Drug interactions
Cyproheptadine + Hops
Severity: Minor
Cyproheptadine and Hops: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Hops has mild sedative properties, and cyproheptadine is a sedating first-generation antihistamine. Taken together they may produce greater drowsiness and impaired psychomotor performance than either alone.
What this interaction means in plain words
Cyproheptadine and Hops have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Additive CNS depressant effects (pharmacodynamic synergism).
What to do
Advise patients to watch for excess drowsiness and to avoid driving or operating machinery until the response is known. Reduce or stop the herbal product if sedation is troublesome.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Cyproheptadine
- Cyproheptadine + Isocarboxazid Contraindicated
- Cyproheptadine + Phenelzine Contraindicated
- Cyproheptadine + Tranylcypromine Contraindicated
- Alfentanil + Cyproheptadine Major
- Belladonna and opium + Cyproheptadine Major
- Benzhydrocodone / acetaminophen + Cyproheptadine Major
Frequently asked questions
Can I take Cyproheptadine with Hops?
MediHelp rates the interaction as minor. Cyproheptadine and Hops have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Hops has mild sedative properties, and cyproheptadine is a sedating first-generation antihistamine. Taken together they may produce greater drowsiness and impaired psychomotor performance than either alone.
How serious is the interaction between Cyproheptadine and Hops?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to watch for excess drowsiness and to avoid driving or operating machinery until the response is known. Reduce or stop the herbal product if sedation is troublesome.
What other medicines interact with Cyproheptadine?
MediHelp also lists interactions of Cyproheptadine with, for example, Isocarboxazid, Phenelzine, Tranylcypromine. The full list is on the Cyproheptadine page.
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