Drug interactions
dabigatran + ketoconazole
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Overview
↑ dabigatran → bleeding risk (esp. renal impairment).
Mechanism of action
P-gp inhibition.
Clinical management
Avoid; if used, consider dose adjustment per label.
Drug reference
References
Frequently asked questions
Can I take dabigatran with ketoconazole?
The interaction is rated: Major. ↑ dabigatran → bleeding risk (esp. renal impairment).
How serious is the interaction between dabigatran and ketoconazole?
The interaction is rated: Major. Evidence level: High.
How is the interaction between dabigatran and ketoconazole managed?
Avoid; if used, consider dose adjustment per label.
Why do dabigatran and ketoconazole interact?
P-gp inhibition.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.