Drug interactions
Dabigatran etexilate + Dong quai
Severity: Moderate
Dabigatran etexilate and Dong quai: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Dong quai contains coumarin-type constituents and has been linked to increased INR with warfarin and possible antiplatelet effects. Combined with dabigatran it may add to bleeding risk, although direct data are lacking.
What this interaction means in plain words
Dabigatran etexilate and Dong quai can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Possible additive pharmacodynamic effect through coumarin-like and antiplatelet constituents; not well established for thrombin inhibitors.
What to do
Advise patients to avoid dong quai while on dabigatran. If used, monitor for bruising, bleeding and falls in hemoglobin.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Dabigatran etexilate
- Dabigatran etexilate + Defibrotide Contraindicated
- Dabigatran etexilate + Ketorolac Contraindicated
- Dabigatran etexilate + Mifepristone Contraindicated
- Abciximab + Dabigatran etexilate Major
- Alteplase + Dabigatran etexilate Major
- Amiodarone + Dabigatran etexilate Major
Frequently asked questions
Can I take Dabigatran etexilate with Dong quai?
MediHelp rates the interaction as moderate. Dabigatran etexilate and Dong quai can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Dong quai contains coumarin-type constituents and has been linked to increased INR with warfarin and possible antiplatelet effects. Combined with dabigatran it may add to bleeding risk, although direct data are lacking.
How serious is the interaction between Dabigatran etexilate and Dong quai?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to avoid dong quai while on dabigatran. If used, monitor for bruising, bleeding and falls in hemoglobin.
What other medicines interact with Dabigatran etexilate?
MediHelp also lists interactions of Dabigatran etexilate with, for example, Defibrotide, Ketorolac, Mifepristone. The full list is on the Dabigatran etexilate page.
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