Drug interactions
Dabigatran etexilate + Ethanol
Severity: Moderate
Dabigatran etexilate and Ethanol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Heavy or acute alcohol intake can irritate the gastrointestinal mucosa and impair hemostasis and judgment, increasing the risk of bleeding and trauma in anticoagulated patients. No direct pharmacokinetic interaction is firmly established.
What this interaction means in plain words
Dabigatran etexilate and Ethanol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Not clearly established; likely additive bleeding risk from GI mucosal injury, platelet effects and falls.
What to do
Counsel patients to avoid binge drinking and keep alcohol intake minimal. Monitor for bleeding in heavy drinkers.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Dabigatran etexilate
- Dabigatran etexilate + Defibrotide Contraindicated
- Dabigatran etexilate + Ketorolac Contraindicated
- Dabigatran etexilate + Mifepristone Contraindicated
- Abciximab + Dabigatran etexilate Major
- Alteplase + Dabigatran etexilate Major
- Amiodarone + Dabigatran etexilate Major
Frequently asked questions
Can I take Dabigatran etexilate with Ethanol?
MediHelp rates the interaction as moderate. Dabigatran etexilate and Ethanol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Heavy or acute alcohol intake can irritate the gastrointestinal mucosa and impair hemostasis and judgment, increasing the risk of bleeding and trauma in anticoagulated patients. No direct pharmacokinetic interaction is firmly established.
How serious is the interaction between Dabigatran etexilate and Ethanol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel patients to avoid binge drinking and keep alcohol intake minimal. Monitor for bleeding in heavy drinkers.
What other medicines interact with Dabigatran etexilate?
MediHelp also lists interactions of Dabigatran etexilate with, for example, Defibrotide, Ketorolac, Mifepristone. The full list is on the Dabigatran etexilate page.
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