Drug interactions
Dabigatran etexilate + Ginkgo biloba
Severity: Moderate
Dabigatran etexilate and Ginkgo biloba: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ginkgo biloba inhibits platelet-activating factor and has been associated with isolated reports of bleeding. With dabigatran it may modestly increase bleeding risk, although controlled data are inconsistent.
What this interaction means in plain words
Dabigatran etexilate and Ginkgo biloba can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Possible additive antiplatelet effect through platelet-activating factor antagonism by ginkgolides.
What to do
Advise patients to avoid ginkgo while taking dabigatran. If it is continued, monitor for bleeding and bruising.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Dabigatran etexilate
- Dabigatran etexilate + Defibrotide Contraindicated
- Dabigatran etexilate + Ketorolac Contraindicated
- Dabigatran etexilate + Mifepristone Contraindicated
- Abciximab + Dabigatran etexilate Major
- Alteplase + Dabigatran etexilate Major
- Amiodarone + Dabigatran etexilate Major
Frequently asked questions
Can I take Dabigatran etexilate with Ginkgo biloba?
MediHelp rates the interaction as moderate. Dabigatran etexilate and Ginkgo biloba can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Ginkgo biloba inhibits platelet-activating factor and has been associated with isolated reports of bleeding. With dabigatran it may modestly increase bleeding risk, although controlled data are inconsistent.
How serious is the interaction between Dabigatran etexilate and Ginkgo biloba?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to avoid ginkgo while taking dabigatran. If it is continued, monitor for bleeding and bruising.
What other medicines interact with Dabigatran etexilate?
MediHelp also lists interactions of Dabigatran etexilate with, for example, Defibrotide, Ketorolac, Mifepristone. The full list is on the Dabigatran etexilate page.
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