Drug interactions
Dabigatran etexilate + Iloprost inhaled
Severity: Moderate
Dabigatran etexilate and Iloprost inhaled: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Iloprost inhibits platelet aggregation, which may add to the bleeding risk of dabigatran. Systemic exposure from inhalation is limited, so the effect is likely modest.
What this interaction means in plain words
Dabigatran etexilate and Iloprost inhaled can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive effect of prostacyclin-mediated platelet inhibition and thrombin inhibition.
What to do
Monitor for bleeding, including hemoptysis, during combined therapy.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Dabigatran etexilate
- Dabigatran etexilate + Defibrotide Contraindicated
- Dabigatran etexilate + Ketorolac Contraindicated
- Dabigatran etexilate + Mifepristone Contraindicated
- Abciximab + Dabigatran etexilate Major
- Alteplase + Dabigatran etexilate Major
- Amiodarone + Dabigatran etexilate Major
Frequently asked questions
Can I take Dabigatran etexilate with Iloprost inhaled?
MediHelp rates the interaction as moderate. Dabigatran etexilate and Iloprost inhaled can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Iloprost inhibits platelet aggregation, which may add to the bleeding risk of dabigatran. Systemic exposure from inhalation is limited, so the effect is likely modest.
How serious is the interaction between Dabigatran etexilate and Iloprost inhaled?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for bleeding, including hemoptysis, during combined therapy.
What other medicines interact with Dabigatran etexilate?
MediHelp also lists interactions of Dabigatran etexilate with, for example, Defibrotide, Ketorolac, Mifepristone. The full list is on the Dabigatran etexilate page.
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