Drug interactions
Danazol + Insulin degludec-liraglutide
Severity: Moderate
Danazol and Insulin degludec-liraglutide: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Danazol can cause insulin resistance and impair glucose tolerance. Patients on insulin may need higher doses to maintain control.
What this interaction means in plain words
Danazol and Insulin degludec-liraglutide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Danazol, an androgenic steroid, reduces insulin sensitivity, antagonizing antidiabetic effects.
What to do
Monitor blood glucose when starting or stopping danazol. Adjust the insulin dose as required.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Insulin degludec-liraglutide
Frequently asked questions
Can I take Danazol with Insulin degludec-liraglutide?
MediHelp rates the interaction as moderate. Danazol and Insulin degludec-liraglutide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Danazol can cause insulin resistance and impair glucose tolerance. Patients on insulin may need higher doses to maintain control.
How serious is the interaction between Danazol and Insulin degludec-liraglutide?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when starting or stopping danazol. Adjust the insulin dose as required.
What other medicines interact with Insulin degludec-liraglutide?
MediHelp also lists interactions of Insulin degludec-liraglutide with, for example, Albiglutide, Chlorpropamide, Clozapine. The full list is on the Insulin degludec-liraglutide page.
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