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Drug interactions

Danazol + Insulin glargine-lixisenatide

Severity: Moderate

Danazol and Insulin glargine-lixisenatide: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Danazol, an androgenic agent, can alter glucose metabolism and cause insulin resistance, so glycemic control may change. Insulin requirements may need adjustment.

What this interaction means in plain words

Danazol and Insulin glargine-lixisenatide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Evidence level: Low

Why it happens

Androgenic effects on insulin sensitivity and glucose metabolism alter the response to insulin.

What to do

Monitor blood glucose when danazol is started, changed or stopped. Adjust the insulin dose according to readings.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Danazol with Insulin glargine-lixisenatide?

MediHelp rates the interaction as moderate. Danazol and Insulin glargine-lixisenatide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Danazol, an androgenic agent, can alter glucose metabolism and cause insulin resistance, so glycemic control may change. Insulin requirements may need adjustment.

How serious is the interaction between Danazol and Insulin glargine-lixisenatide?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when danazol is started, changed or stopped. Adjust the insulin dose according to readings.

What other medicines interact with Insulin glargine-lixisenatide?

MediHelp also lists interactions of Insulin glargine-lixisenatide with, for example, Albiglutide, Chlorpropamide, Dulaglutide. The full list is on the Insulin glargine-lixisenatide page.

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