Drug interactions
Danazol + Insulin glulisine
Severity: Moderate
Danazol and Insulin glulisine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Danazol, an androgenic agent, can cause insulin resistance and impair glucose tolerance, so insulin requirements may change. Glycemic control may worsen during therapy.
What this interaction means in plain words
Danazol and Insulin glulisine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Androgenic effects cause insulin resistance, altering the response to insulin.
What to do
Monitor blood glucose when starting or stopping danazol and adjust the insulin dose accordingly.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Insulin glulisine
Frequently asked questions
Can I take Danazol with Insulin glulisine?
MediHelp rates the interaction as moderate. Danazol and Insulin glulisine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Danazol, an androgenic agent, can cause insulin resistance and impair glucose tolerance, so insulin requirements may change. Glycemic control may worsen during therapy.
How serious is the interaction between Danazol and Insulin glulisine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when starting or stopping danazol and adjust the insulin dose accordingly.
What other medicines interact with Insulin glulisine?
MediHelp also lists interactions of Insulin glulisine with, for example, Alogliptin-pioglitazone, Ethanol, Pentamidine. The full list is on the Insulin glulisine page.
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