Drug interactions
Danazol + Levonorgestrel
Severity: Minor
Danazol and Levonorgestrel: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Danazol weakly inhibits CYP3A4 and might slightly raise levonorgestrel exposure. Clinical relevance is minimal, especially with an intrauterine system.
What this interaction means in plain words
Danazol and Levonorgestrel have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Weak CYP3A4 inhibition by danazol.
What to do
No specific action needed beyond awareness.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Levonorgestrel
Frequently asked questions
Can I take Danazol with Levonorgestrel?
MediHelp rates the interaction as minor. Danazol and Levonorgestrel have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Danazol weakly inhibits CYP3A4 and might slightly raise levonorgestrel exposure. Clinical relevance is minimal, especially with an intrauterine system.
How serious is the interaction between Danazol and Levonorgestrel?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No specific action needed beyond awareness.
What other medicines interact with Levonorgestrel?
MediHelp also lists interactions of Levonorgestrel with, for example, Amobarbital, Apalutamide, Belzutifan. The full list is on the Levonorgestrel page.
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