Drug reference

levonorgestrel

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Drug class

Endocrine (Progestin Preparations)

Mechanism of action

Oral: Synthetic progestin, ovulation is inhibited from a negative feedback mechanism on hypothalamus, leading to reduced secretion of FSH and LH. Suggested mechanisms of preventing pregnancy are thickening of cervical mucus preventing passage of sperm into the uterus, inhibition of sperm capacitation or survival, and alteration of the endometrium

Common side effects

  • Headache
  • Acne
  • Unscheduled uterine bleeding
  • Amenorrhea
  • Decreased uterine bleeding
  • Ovarian cysts
  • Enlarged follicles

Related conditions

Frequently asked questions

What drug class is levonorgestrel?

levonorgestrel belongs to: Endocrine.

How does levonorgestrel work?

Oral: Synthetic progestin, ovulation is inhibited from a negative feedback mechanism on hypothalamus, leading to reduced secretion of FSH and LH. Suggested mechanisms of preventing pregnancy are thickening of cervical mucus preventing passage of sperm into the uterus, inhibition of sperm capacitation or survival, and alteration of the endometrium

What are the common side effects of levonorgestrel?

Headache, Acne, Unscheduled uterine bleeding, Amenorrhea, Decreased uterine bleeding, Ovarian cysts, Enlarged follicles

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