Drug interactions
Deferasirox + Enoxaparin
Severity: Moderate
Deferasirox and Enoxaparin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Deferasirox can cause gastrointestinal ulceration and hemorrhage, and it can also lower platelet counts. Enoxaparin may make any such bleeding more severe.
What this interaction means in plain words
Deferasirox and Enoxaparin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Deferasirox belongs to Miscellaneous; Enoxaparin belongs to Cardiovascular.
Why it happens
Deferasirox-related mucosal injury and possible cytopenia combine with the anticoagulant effect of enoxaparin to raise bleeding risk.
What to do
Monitor for gastrointestinal bleeding and follow platelet counts and hemoglobin. Consider gastroprotection and stop deferasirox if ulceration or bleeding occurs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Enoxaparin
- Defibrotide + Enoxaparin Contraindicated
- Enoxaparin + Ketorolac Contraindicated
- Enoxaparin + Mifepristone Contraindicated
- Abciximab + Enoxaparin Major
- Aceclofenac + Enoxaparin Major
- Acetylsalicylic acid + Enoxaparin Major
Other interactions of Deferasirox
Frequently asked questions
Can I take Deferasirox with Enoxaparin?
MediHelp rates the interaction as moderate. Deferasirox and Enoxaparin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Deferasirox can cause gastrointestinal ulceration and hemorrhage, and it can also lower platelet counts. Enoxaparin may make any such bleeding more severe.
How serious is the interaction between Deferasirox and Enoxaparin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for gastrointestinal bleeding and follow platelet counts and hemoglobin. Consider gastroprotection and stop deferasirox if ulceration or bleeding occurs.
What other medicines interact with Enoxaparin?
MediHelp also lists interactions of Enoxaparin with, for example, Defibrotide, Ketorolac, Mifepristone. The full list is on the Enoxaparin page.
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