Drug interactions
Deferasirox + Erythromycin
Severity: Minor
Deferasirox and Erythromycin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Deferasirox may lower erythromycin concentrations, reducing antibacterial effect. The effect of deferasirox on CYP3A4 is variable, and erythromycin may also affect deferasirox exposure only slightly.
What this interaction means in plain words
Deferasirox and Erythromycin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Deferasirox belongs to Miscellaneous; Erythromycin belongs to Anti Bacterial.
Why it happens
Deferasirox induces CYP3A4 weakly, which may increase erythromycin metabolism.
What to do
Monitor clinical response to the antibiotic; no empirical dose change is generally required.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Erythromycin
- Conivaptan + Erythromycin Contraindicated
- Dihydroergotamine intranasal + Erythromycin Contraindicated
- Dihydroergotamine + Erythromycin Contraindicated
- Domperidone + Erythromycin Contraindicated
- Dronedarone + Erythromycin Contraindicated
- Droperidol + Erythromycin Contraindicated
Other interactions of Deferasirox
Frequently asked questions
Can I take Deferasirox with Erythromycin?
MediHelp rates the interaction as minor. Deferasirox and Erythromycin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Deferasirox may lower erythromycin concentrations, reducing antibacterial effect. The effect of deferasirox on CYP3A4 is variable, and erythromycin may also affect deferasirox exposure only slightly.
How serious is the interaction between Deferasirox and Erythromycin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor clinical response to the antibiotic; no empirical dose change is generally required.
What other medicines interact with Erythromycin?
MediHelp also lists interactions of Erythromycin with, for example, Conivaptan, Dihydroergotamine intranasal, Dihydroergotamine. The full list is on the Erythromycin page.
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