Drug interactions
Deferasirox + Nifedipine
Severity: Minor
Deferasirox and Nifedipine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Deferasirox may reduce nifedipine concentrations through CYP3A4 induction, though the effect is variable and not well characterized. Reduced blood pressure or angina control is possible.
What this interaction means in plain words
Deferasirox and Nifedipine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Deferasirox belongs to Miscellaneous; Nifedipine belongs to Cardiovascular.
Why it happens
Possible CYP3A4 induction by deferasirox increasing nifedipine metabolism.
What to do
Monitor blood pressure and anginal symptoms. Increase the nifedipine dose if control is lost.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Nifedipine
Other interactions of Deferasirox
Frequently asked questions
Can I take Deferasirox with Nifedipine?
MediHelp rates the interaction as minor. Deferasirox and Nifedipine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Deferasirox may reduce nifedipine concentrations through CYP3A4 induction, though the effect is variable and not well characterized. Reduced blood pressure or angina control is possible.
How serious is the interaction between Deferasirox and Nifedipine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and anginal symptoms. Increase the nifedipine dose if control is lost.
What other medicines interact with Nifedipine?
MediHelp also lists interactions of Nifedipine with, for example, Amifostine, Amlodipine-benazepril, Apalutamide. The full list is on the Nifedipine page.
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