Drug interactions
Deferasirox + Sunitinib
Severity: Minor
Deferasirox and Sunitinib: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Deferasirox has variable effects on CYP enzymes, inducing CYP3A4 in some settings, and could lower sunitinib exposure. The magnitude is uncertain and the clinical relevance is probably modest.
What this interaction means in plain words
Deferasirox and Sunitinib have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Deferasirox belongs to Miscellaneous; Sunitinib belongs to Oncology.
Why it happens
Possible CYP3A4 induction by deferasirox increasing sunitinib metabolism; not firmly established.
What to do
Monitor treatment response when starting or stopping deferasirox. Adjust sunitinib only if loss of efficacy is evident.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Sunitinib
- Adagrasib + Sunitinib Major
- Amiodarone + Sunitinib Major
- Amisulpride + Sunitinib Major
- Anagrelide + Sunitinib Major
- Apalutamide + Sunitinib Major
- Arsenic trioxide + Sunitinib Major
Other interactions of Deferasirox
Frequently asked questions
Can I take Deferasirox with Sunitinib?
MediHelp rates the interaction as minor. Deferasirox and Sunitinib have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Deferasirox has variable effects on CYP enzymes, inducing CYP3A4 in some settings, and could lower sunitinib exposure. The magnitude is uncertain and the clinical relevance is probably modest.
How serious is the interaction between Deferasirox and Sunitinib?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor treatment response when starting or stopping deferasirox. Adjust sunitinib only if loss of efficacy is evident.
What other medicines interact with Sunitinib?
MediHelp also lists interactions of Sunitinib with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Sunitinib page.
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