Drug interactions
Deferasirox + Tiludronate
Severity: Moderate
Deferasirox and Tiludronate: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Oral tiludronate and deferasirox can both irritate the gastrointestinal tract. Together they may raise the risk of ulceration and bleeding.
What this interaction means in plain words
Deferasirox and Tiludronate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Deferasirox belongs to Miscellaneous; Tiludronate belongs to Musculoskeletal.
Why it happens
Additive gastrointestinal mucosal irritation.
What to do
Monitor for GI symptoms or bleeding and stop tiludronate if upper GI symptoms develop.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Tiludronate
- Acetylsalicylic acid + Tiludronate Moderate
- Aluminum hydroxide + Tiludronate Moderate
- Calcium acetate + Tiludronate Moderate
- Calcium carbonate + Tiludronate Moderate
- Calcium chloride + Tiludronate Moderate
- Calcium citrate + Tiludronate Moderate
Other interactions of Deferasirox
Frequently asked questions
Can I take Deferasirox with Tiludronate?
MediHelp rates the interaction as moderate. Deferasirox and Tiludronate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oral tiludronate and deferasirox can both irritate the gastrointestinal tract. Together they may raise the risk of ulceration and bleeding.
How serious is the interaction between Deferasirox and Tiludronate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for GI symptoms or bleeding and stop tiludronate if upper GI symptoms develop.
What other medicines interact with Tiludronate?
MediHelp also lists interactions of Tiludronate with, for example, Acetylsalicylic acid, Aluminum hydroxide, Calcium acetate. The full list is on the Tiludronate page.
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