Drug interactions
Deferasirox + Tirofiban
Severity: Moderate
Deferasirox and Tirofiban: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Deferasirox can cause gastric ulceration and GI hemorrhage. Tirofiban's strong platelet inhibition may make bleeding from such lesions more severe.
What this interaction means in plain words
Deferasirox and Tirofiban can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Deferasirox belongs to Miscellaneous; Tirofiban belongs to Cardiovascular.
Why it happens
Deferasirox-related GI mucosal injury combined with tirofiban's antiplatelet effect increases hemorrhage risk.
What to do
Monitor for GI bleeding signs and hemoglobin during co-administration. Consider a proton pump inhibitor in higher-risk patients.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Deferasirox and Tirofiban, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Tirofiban
Other interactions of Deferasirox
Frequently asked questions
Can I take Deferasirox with Tirofiban?
MediHelp rates the interaction as moderate. Deferasirox and Tirofiban can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Deferasirox can cause gastric ulceration and GI hemorrhage. Tirofiban's strong platelet inhibition may make bleeding from such lesions more severe.
How serious is the interaction between Deferasirox and Tirofiban?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for GI bleeding signs and hemoglobin during co-administration. Consider a proton pump inhibitor in higher-risk patients.
What other medicines interact with Tirofiban?
MediHelp also lists interactions of Tirofiban with, for example, Abrocitinib, Acalabrutinib, Acetylsalicylic acid. The full list is on the Tirofiban page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
