Drug interactions
Deferiprone + Interferon gamma 1b
Severity: Moderate
Deferiprone and Interferon gamma 1b: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Interferon gamma-1b can occasionally cause neutropenia, though less often than other interferons. With deferiprone, additive neutropenia is possible.
What this interaction means in plain words
Deferiprone and Interferon gamma 1b can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Possible additive neutropenic effects.
What to do
Monitor absolute neutrophil count more frequently during concurrent therapy and stop deferiprone if neutropenia develops.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Deferiprone
- Clozapine + Deferiprone Contraindicated
- Abemaciclib + Deferiprone Major
- Acalabrutinib + Deferiprone Major
- Ado-trastuzumab emtansine + Deferiprone Major
- Ado-trastuzumab + Deferiprone Major
- Aldesleukin + Deferiprone Major
Frequently asked questions
Can I take Deferiprone with Interferon gamma 1b?
MediHelp rates the interaction as moderate. Deferiprone and Interferon gamma 1b can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Interferon gamma-1b can occasionally cause neutropenia, though less often than other interferons. With deferiprone, additive neutropenia is possible.
How serious is the interaction between Deferiprone and Interferon gamma 1b?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor absolute neutrophil count more frequently during concurrent therapy and stop deferiprone if neutropenia develops.
What other medicines interact with Deferiprone?
MediHelp also lists interactions of Deferiprone with, for example, Clozapine, Abemaciclib, Acalabrutinib. The full list is on the Deferiprone page.
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