Drug interactions
Deferiprone + Magnesium salicylate
Severity: Minor
Deferiprone and Magnesium salicylate: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Magnesium salicylate supplies magnesium ions that can bind deferiprone in the gut lumen. This may lower deferiprone absorption and reduce its iron-removing effect.
What this interaction means in plain words
Deferiprone and Magnesium salicylate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Chelation of deferiprone by magnesium in the gastrointestinal tract reduces oral absorption.
What to do
Separate administration of deferiprone and magnesium salicylate by at least 4 hours. Monitor serum ferritin if both are used long term.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Deferiprone
- Clozapine + Deferiprone Contraindicated
- Abemaciclib + Deferiprone Major
- Acalabrutinib + Deferiprone Major
- Ado-trastuzumab emtansine + Deferiprone Major
- Ado-trastuzumab + Deferiprone Major
- Aldesleukin + Deferiprone Major
Frequently asked questions
Can I take Deferiprone with Magnesium salicylate?
MediHelp rates the interaction as minor. Deferiprone and Magnesium salicylate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Magnesium salicylate supplies magnesium ions that can bind deferiprone in the gut lumen. This may lower deferiprone absorption and reduce its iron-removing effect.
How serious is the interaction between Deferiprone and Magnesium salicylate?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate administration of deferiprone and magnesium salicylate by at least 4 hours. Monitor serum ferritin if both are used long term.
What other medicines interact with Deferiprone?
MediHelp also lists interactions of Deferiprone with, for example, Clozapine, Abemaciclib, Acalabrutinib. The full list is on the Deferiprone page.
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