Drug interactions
Deferiprone + Sodium sulfate / ?magnesium sulfate / potassium chloride
Severity: Minor
Deferiprone and Sodium sulfate / ?magnesium sulfate / potassium chloride: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
This bowel preparation contains magnesium that can bind deferiprone in the gut. Taken together, it may reduce deferiprone absorption, and the rapid transit caused by the laxative effect may also lower exposure.
What this interaction means in plain words
Deferiprone and Sodium sulfate / ?magnesium sulfate / potassium chloride have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Magnesium chelates deferiprone in the intestine, and laxative-induced rapid transit may further reduce absorption.
What to do
Give deferiprone at least 2 hours before or after each dose of the bowel preparation.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Deferiprone
- Clozapine + Deferiprone Contraindicated
- Abemaciclib + Deferiprone Major
- Acalabrutinib + Deferiprone Major
- Ado-trastuzumab emtansine + Deferiprone Major
- Ado-trastuzumab + Deferiprone Major
- Aldesleukin + Deferiprone Major
Frequently asked questions
Can I take Deferiprone with Sodium sulfate / ?magnesium sulfate / potassium chloride?
MediHelp rates the interaction as minor. Deferiprone and Sodium sulfate / ?magnesium sulfate / potassium chloride have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. This bowel preparation contains magnesium that can bind deferiprone in the gut. Taken together, it may reduce deferiprone absorption, and the rapid transit caused by the laxative effect may also lower exposure.
How serious is the interaction between Deferiprone and Sodium sulfate / ?magnesium sulfate / potassium chloride?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give deferiprone at least 2 hours before or after each dose of the bowel preparation.
What other medicines interact with Deferiprone?
MediHelp also lists interactions of Deferiprone with, for example, Clozapine, Abemaciclib, Acalabrutinib. The full list is on the Deferiprone page.
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