Drug interactions
Deferiprone + Streptozocin
Severity: Moderate
Deferiprone and Streptozocin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Streptozocin can cause hematologic toxicity as well as renal toxicity. Used with deferiprone, additive suppression of blood counts is possible.
What this interaction means in plain words
Deferiprone and Streptozocin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Possible additive myelosuppression.
What to do
Monitor absolute neutrophil count and complete blood counts more often during combined use. Stop deferiprone if neutropenia develops.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Deferiprone
- Clozapine + Deferiprone Contraindicated
- Abemaciclib + Deferiprone Major
- Acalabrutinib + Deferiprone Major
- Ado-trastuzumab emtansine + Deferiprone Major
- Ado-trastuzumab + Deferiprone Major
- Aldesleukin + Deferiprone Major
Frequently asked questions
Can I take Deferiprone with Streptozocin?
MediHelp rates the interaction as moderate. Deferiprone and Streptozocin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Streptozocin can cause hematologic toxicity as well as renal toxicity. Used with deferiprone, additive suppression of blood counts is possible.
How serious is the interaction between Deferiprone and Streptozocin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor absolute neutrophil count and complete blood counts more often during combined use. Stop deferiprone if neutropenia develops.
What other medicines interact with Deferiprone?
MediHelp also lists interactions of Deferiprone with, for example, Clozapine, Abemaciclib, Acalabrutinib. The full list is on the Deferiprone page.
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