Drug interactions
Deflazacort + Human papillomavirus vaccine nonavalent
Severity: Minor
Deflazacort and Human papillomavirus vaccine nonavalent: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Corticosteroids at greater than physiologic doses can reduce the immune response to vaccines. Antibody response to the HPV vaccine may be diminished, though it is a non-live vaccine and is not unsafe.
What this interaction means in plain words
Deflazacort and Human papillomavirus vaccine nonavalent have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Corticosteroid-mediated immunosuppression blunts the vaccine immune response.
What to do
Vaccination need not be withheld; give the vaccine as scheduled, ideally before starting long-term steroids when feasible. Consider checking response or revaccination per local guidance.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Deflazacort and Human papillomavirus vaccine nonavalent, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Deflazacort
- Adenovirus types 4 and 7 live + Deflazacort Contraindicated
- Bcg vaccine live + Deflazacort Contraindicated
- Deflazacort + Influenza virus vaccine quadrivalent intranasal Contraindicated
- Deflazacort + Measles mumps and rubella vaccine Contraindicated
- Deflazacort + Measles mumps and rubella vaccine live Contraindicated
- Deflazacort + Measles mumps rubella and varicella vaccine live Contraindicated
Frequently asked questions
Can I take Deflazacort with Human papillomavirus vaccine nonavalent?
MediHelp rates the interaction as minor. Deflazacort and Human papillomavirus vaccine nonavalent have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Corticosteroids at greater than physiologic doses can reduce the immune response to vaccines. Antibody response to the HPV vaccine may be diminished, though it is a non-live vaccine and is not unsafe.
How serious is the interaction between Deflazacort and Human papillomavirus vaccine nonavalent?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Vaccination need not be withheld; give the vaccine as scheduled, ideally before starting long-term steroids when feasible. Consider checking response or revaccination per local guidance.
What other medicines interact with Deflazacort?
MediHelp also lists interactions of Deflazacort with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Deflazacort page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
