Drug interactions
Deflazacort + Insulin neutral human
Severity: Moderate
Deflazacort and Insulin neutral human: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Deflazacort is a glucocorticoid that raises blood glucose and can reduce the effectiveness of insulin, so insulin requirements often rise. Both agents can also lower serum potassium.
What this interaction means in plain words
Deflazacort and Insulin neutral human can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Deflazacort belongs to Miscellaneous; Insulin neutral human belongs to Endocrine.
Why it happens
Glucocorticoids induce insulin resistance and increase hepatic gluconeogenesis; both drugs also shift or lose potassium.
What to do
Monitor glucose and increase insulin as needed when deflazacort is started, then reduce it as the steroid is tapered. Check serum potassium periodically.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Insulin neutral human
Other interactions of Deflazacort
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- Bcg vaccine live + Deflazacort Contraindicated
- Deflazacort + Influenza virus vaccine quadrivalent intranasal Contraindicated
- Deflazacort + Measles mumps and rubella vaccine Contraindicated
- Deflazacort + Measles mumps and rubella vaccine live Contraindicated
- Deflazacort + Measles mumps rubella and varicella vaccine live Contraindicated
Frequently asked questions
Can I take Deflazacort with Insulin neutral human?
MediHelp rates the interaction as moderate. Deflazacort and Insulin neutral human can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Deflazacort is a glucocorticoid that raises blood glucose and can reduce the effectiveness of insulin, so insulin requirements often rise. Both agents can also lower serum potassium.
How serious is the interaction between Deflazacort and Insulin neutral human?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor glucose and increase insulin as needed when deflazacort is started, then reduce it as the steroid is tapered. Check serum potassium periodically.
What other medicines interact with Insulin neutral human?
MediHelp also lists interactions of Insulin neutral human with, for example, Chlorpropamide, Ethanol, Mecasermin. The full list is on the Insulin neutral human page.
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