Drug interactions
Deflazacort + Polyethylene glycol / electrolytes / sodium ascorbate / ascorbic acid
Severity: Moderate
Deflazacort and Polyethylene glycol / electrolytes / sodium ascorbate / ascorbic acid: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
This bowel-cleansing preparation causes fluid shifts and gastrointestinal electrolyte losses. Deflazacort adds renal potassium wasting, which can contribute to hypokalemia and dehydration.
What this interaction means in plain words
Deflazacort and Polyethylene glycol / electrolytes / sodium ascorbate / ascorbic acid can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive potassium depletion from bowel-preparation losses and corticosteroid-induced renal potassium excretion.
What to do
Maintain hydration and check serum electrolytes in at-risk patients, such as those with heart disease or taking other drugs that lower potassium, and correct deficits.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Deflazacort and Polyethylene glycol / electrolytes / sodium ascorbate / ascorbic acid, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Deflazacort
- Adenovirus types 4 and 7 live + Deflazacort Contraindicated
- Bcg vaccine live + Deflazacort Contraindicated
- Deflazacort + Influenza virus vaccine quadrivalent intranasal Contraindicated
- Deflazacort + Measles mumps and rubella vaccine Contraindicated
- Deflazacort + Measles mumps and rubella vaccine live Contraindicated
- Deflazacort + Measles mumps rubella and varicella vaccine live Contraindicated
Frequently asked questions
Can I take Deflazacort with Polyethylene glycol / electrolytes / sodium ascorbate / ascorbic acid?
MediHelp rates the interaction as moderate. Deflazacort and Polyethylene glycol / electrolytes / sodium ascorbate / ascorbic acid can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. This bowel-cleansing preparation causes fluid shifts and gastrointestinal electrolyte losses. Deflazacort adds renal potassium wasting, which can contribute to hypokalemia and dehydration.
How serious is the interaction between Deflazacort and Polyethylene glycol / electrolytes / sodium ascorbate / ascorbic acid?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Maintain hydration and check serum electrolytes in at-risk patients, such as those with heart disease or taking other drugs that lower potassium, and correct deficits.
What other medicines interact with Deflazacort?
MediHelp also lists interactions of Deflazacort with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Deflazacort page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
