Drug interactions
Deflazacort + Schisandra
Severity: Minor
Deflazacort and Schisandra: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Schisandra constituents inhibit CYP3A4 in vitro and in some human data, so deflazacort exposure might rise. Clinical significance is uncertain.
What this interaction means in plain words
Deflazacort and Schisandra have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible CYP3A4 inhibition by schisandra lignans.
What to do
Monitor for corticosteroid adverse effects if schisandra is used regularly with deflazacort.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Deflazacort
- Adenovirus types 4 and 7 live + Deflazacort Contraindicated
- Bcg vaccine live + Deflazacort Contraindicated
- Deflazacort + Influenza virus vaccine quadrivalent intranasal Contraindicated
- Deflazacort + Measles mumps and rubella vaccine Contraindicated
- Deflazacort + Measles mumps and rubella vaccine live Contraindicated
- Deflazacort + Measles mumps rubella and varicella vaccine live Contraindicated
Frequently asked questions
Can I take Deflazacort with Schisandra?
MediHelp rates the interaction as minor. Deflazacort and Schisandra have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Schisandra constituents inhibit CYP3A4 in vitro and in some human data, so deflazacort exposure might rise. Clinical significance is uncertain.
How serious is the interaction between Deflazacort and Schisandra?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for corticosteroid adverse effects if schisandra is used regularly with deflazacort.
What other medicines interact with Deflazacort?
MediHelp also lists interactions of Deflazacort with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Deflazacort page.
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