Drug interactions
Deflazacort + Senna
Severity: Minor
Deflazacort and Senna: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Chronic or excessive senna use causes diarrhea and potassium loss, which can add to the potassium-wasting effect of corticosteroids. Resulting hypokalemia may cause weakness or arrhythmias.
What this interaction means in plain words
Deflazacort and Senna have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Deflazacort belongs to Miscellaneous; Senna belongs to Gastrointestinal Tract.
Why it happens
Additive potassium depletion from stimulant laxative-induced intestinal losses and corticosteroid-driven renal excretion.
What to do
Avoid prolonged laxative use and monitor serum potassium if used chronically.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Deflazacort and Senna, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 14 days on the web. No card needed.
Other interactions of Deflazacort
- Adenovirus types 4 and 7 live + Deflazacort Contraindicated
- Bcg vaccine live + Deflazacort Contraindicated
- Deflazacort + Influenza virus vaccine quadrivalent intranasal Contraindicated
- Deflazacort + Measles mumps and rubella vaccine Contraindicated
- Deflazacort + Measles mumps and rubella vaccine live Contraindicated
- Deflazacort + Measles mumps rubella and varicella vaccine live Contraindicated
Other interactions of Senna
Frequently asked questions
Can I take Deflazacort with Senna?
MediHelp rates the interaction as minor. Deflazacort and Senna have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Chronic or excessive senna use causes diarrhea and potassium loss, which can add to the potassium-wasting effect of corticosteroids. Resulting hypokalemia may cause weakness or arrhythmias.
How serious is the interaction between Deflazacort and Senna?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid prolonged laxative use and monitor serum potassium if used chronically.
What other medicines interact with Deflazacort?
MediHelp also lists interactions of Deflazacort with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Deflazacort page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
