Drug interactions
Deflazacort + Sodium phosphate rectal
Severity: Minor
Deflazacort and Sodium phosphate rectal: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Sodium phosphate enemas can cause fluid and electrolyte disturbances, including hypokalemia, particularly if retained or overused. Corticosteroid-induced potassium loss may add to this effect.
What this interaction means in plain words
Deflazacort and Sodium phosphate rectal have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Additive electrolyte disturbance from osmotic fluid shifts and corticosteroid-induced renal potassium wasting.
What to do
Avoid repeated enema dosing and check electrolytes in patients with renal impairment or on long-term corticosteroids.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Deflazacort
- Adenovirus types 4 and 7 live + Deflazacort Contraindicated
- Bcg vaccine live + Deflazacort Contraindicated
- Deflazacort + Influenza virus vaccine quadrivalent intranasal Contraindicated
- Deflazacort + Measles mumps and rubella vaccine Contraindicated
- Deflazacort + Measles mumps and rubella vaccine live Contraindicated
- Deflazacort + Measles mumps rubella and varicella vaccine live Contraindicated
Frequently asked questions
Can I take Deflazacort with Sodium phosphate rectal?
MediHelp rates the interaction as minor. Deflazacort and Sodium phosphate rectal have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Sodium phosphate enemas can cause fluid and electrolyte disturbances, including hypokalemia, particularly if retained or overused. Corticosteroid-induced potassium loss may add to this effect.
How serious is the interaction between Deflazacort and Sodium phosphate rectal?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid repeated enema dosing and check electrolytes in patients with renal impairment or on long-term corticosteroids.
What other medicines interact with Deflazacort?
MediHelp also lists interactions of Deflazacort with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Deflazacort page.
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