Drug interactions
Deflazacort + Travelers diarrhea and cholera vaccine inactivated
Severity: Minor
Deflazacort and Travelers diarrhea and cholera vaccine inactivated: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Corticosteroids suppress immune responses, so the antibody response to an inactivated cholera or travelers' diarrhea vaccine may be weaker in a patient taking deflazacort. Because the vaccine is not live, there is no infection risk, and vaccination is not prohibited.
What this interaction means in plain words
Deflazacort and Travelers diarrhea and cholera vaccine inactivated have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Glucocorticoid-induced immunosuppression may blunt the vaccine-induced immune response.
What to do
Where possible, give the vaccine before starting deflazacort or at the lowest feasible steroid dose, and do not delay travel-related protection unnecessarily. Consider that protection may be reduced and reinforce hygiene measures.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Deflazacort and Travelers diarrhea and cholera vaccine inactivated, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Deflazacort
- Adenovirus types 4 and 7 live + Deflazacort Contraindicated
- Bcg vaccine live + Deflazacort Contraindicated
- Deflazacort + Influenza virus vaccine quadrivalent intranasal Contraindicated
- Deflazacort + Measles mumps and rubella vaccine Contraindicated
- Deflazacort + Measles mumps and rubella vaccine live Contraindicated
- Deflazacort + Measles mumps rubella and varicella vaccine live Contraindicated
Frequently asked questions
Can I take Deflazacort with Travelers diarrhea and cholera vaccine inactivated?
MediHelp rates the interaction as minor. Deflazacort and Travelers diarrhea and cholera vaccine inactivated have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Corticosteroids suppress immune responses, so the antibody response to an inactivated cholera or travelers' diarrhea vaccine may be weaker in a patient taking deflazacort. Because the vaccine is not live, there is no infection risk, and vaccination is not prohibited.
How serious is the interaction between Deflazacort and Travelers diarrhea and cholera vaccine inactivated?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Where possible, give the vaccine before starting deflazacort or at the lowest feasible steroid dose, and do not delay travel-related protection unnecessarily. Consider that protection may be reduced and reinforce hygiene measures.
What other medicines interact with Deflazacort?
MediHelp also lists interactions of Deflazacort with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Deflazacort page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
