Drug interactions
Deflazacort + Willow bark
Severity: Minor
Deflazacort and Willow bark: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Willow bark contains salicin, which is converted to salicylates. Corticosteroids can increase renal salicylate clearance and lower levels, and willow bark may add gastrointestinal irritation risk with a corticosteroid.
What this interaction means in plain words
Deflazacort and Willow bark have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Corticosteroids may increase renal clearance of salicylates.
What to do
Monitor for reduced analgesic effect and for gastrointestinal bleeding symptoms. Take care when stopping the corticosteroid, as salicylate levels may rise.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Deflazacort
- Adenovirus types 4 and 7 live + Deflazacort Contraindicated
- Bcg vaccine live + Deflazacort Contraindicated
- Deflazacort + Influenza virus vaccine quadrivalent intranasal Contraindicated
- Deflazacort + Measles mumps and rubella vaccine Contraindicated
- Deflazacort + Measles mumps and rubella vaccine live Contraindicated
- Deflazacort + Measles mumps rubella and varicella vaccine live Contraindicated
Frequently asked questions
Can I take Deflazacort with Willow bark?
MediHelp rates the interaction as minor. Deflazacort and Willow bark have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Willow bark contains salicin, which is converted to salicylates. Corticosteroids can increase renal salicylate clearance and lower levels, and willow bark may add gastrointestinal irritation risk with a corticosteroid.
How serious is the interaction between Deflazacort and Willow bark?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for reduced analgesic effect and for gastrointestinal bleeding symptoms. Take care when stopping the corticosteroid, as salicylate levels may rise.
What other medicines interact with Deflazacort?
MediHelp also lists interactions of Deflazacort with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Deflazacort page.
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