Drug interactions
Dengue vaccine + Erlotinib
Severity: Moderate
Dengue vaccine and Erlotinib: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Dengue vaccine is a live attenuated vaccine. Erlotinib is not a classic broad immunosuppressant, so the interaction is mainly theoretical, but patients with cancer may have impaired immunity from disease or other therapy.
What this interaction means in plain words
Dengue vaccine and Erlotinib can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Possible reduced immune response and risk of live-vaccine infection in immunocompromised patients; erlotinib itself has no well-established immunosuppressive effect.
What to do
Avoid live vaccines in patients with active cancer on systemic therapy unless the oncologist agrees. Review the patient's overall immune status before vaccination.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Dengue vaccine and Erlotinib, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Erlotinib
- Amobarbital + Erlotinib Major
- Apalutamide + Erlotinib Major
- Carbamazepine + Erlotinib Major
- Cobicistat + Erlotinib Major
- Darunavir + Erlotinib Major
- Dexlansoprazole + Erlotinib Major
Frequently asked questions
Can I take Dengue vaccine with Erlotinib?
MediHelp rates the interaction as moderate. Dengue vaccine and Erlotinib can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Dengue vaccine is a live attenuated vaccine. Erlotinib is not a classic broad immunosuppressant, so the interaction is mainly theoretical, but patients with cancer may have impaired immunity from disease or other therapy.
How serious is the interaction between Dengue vaccine and Erlotinib?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid live vaccines in patients with active cancer on systemic therapy unless the oncologist agrees. Review the patient's overall immune status before vaccination.
What other medicines interact with Erlotinib?
MediHelp also lists interactions of Erlotinib with, for example, Amobarbital, Apalutamide, Carbamazepine. The full list is on the Erlotinib page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
