Drug interactions
Desogestrel-ethinyl estradiol + Exenatide injectable
Severity: Minor
Desogestrel-ethinyl estradiol and Exenatide injectable: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Exenatide slows gastric emptying and may reduce the rate of absorption of oral drugs, and contraceptives can impair glucose tolerance. The clinical effect on contraceptive efficacy is uncertain and likely small.
What this interaction means in plain words
Desogestrel-ethinyl estradiol and Exenatide injectable have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Delayed gastric emptying by exenatide may slow oral contraceptive absorption, and hormones can reduce insulin sensitivity.
What to do
Take the oral contraceptive at least one hour before exenatide injection and monitor glucose control.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Desogestrel-ethinyl estradiol
- Desogestrel-ethinyl estradiol + Fezolinetant Contraindicated
- Aminocaproic acid + Desogestrel-ethinyl estradiol Major
- Amobarbital + Desogestrel-ethinyl estradiol Major
- Anastrozole + Desogestrel-ethinyl estradiol Major
- Apalutamide + Desogestrel-ethinyl estradiol Major
- Atazanavir + Desogestrel-ethinyl estradiol Major
Frequently asked questions
Can I take Desogestrel-ethinyl estradiol with Exenatide injectable?
MediHelp rates the interaction as minor. Desogestrel-ethinyl estradiol and Exenatide injectable have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Exenatide slows gastric emptying and may reduce the rate of absorption of oral drugs, and contraceptives can impair glucose tolerance. The clinical effect on contraceptive efficacy is uncertain and likely small.
How serious is the interaction between Desogestrel-ethinyl estradiol and Exenatide injectable?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Take the oral contraceptive at least one hour before exenatide injection and monitor glucose control.
What other medicines interact with Desogestrel-ethinyl estradiol?
MediHelp also lists interactions of Desogestrel-ethinyl estradiol with, for example, Fezolinetant, Aminocaproic acid, Amobarbital. The full list is on the Desogestrel-ethinyl estradiol page.
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