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Drug interactions

Desvenlafaxine + Fish oil triglycerides

Severity: Minor

Desvenlafaxine and Fish oil triglycerides: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Omega-3 fatty acids have mild antiplatelet effects and desvenlafaxine can impair platelet serotonin uptake, so bleeding tendency may be slightly increased. Clinically significant bleeding is uncommon at usual doses.

What this interaction means in plain words

Desvenlafaxine and Fish oil triglycerides have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

Additive effects on platelet function.

What to do

Be alert for bruising or bleeding, especially if anticoagulants or antiplatelets are also used.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Desvenlafaxine with Fish oil triglycerides?

MediHelp rates the interaction as minor. Desvenlafaxine and Fish oil triglycerides have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Omega-3 fatty acids have mild antiplatelet effects and desvenlafaxine can impair platelet serotonin uptake, so bleeding tendency may be slightly increased. Clinically significant bleeding is uncommon at usual doses.

How serious is the interaction between Desvenlafaxine and Fish oil triglycerides?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Be alert for bruising or bleeding, especially if anticoagulants or antiplatelets are also used.

What other medicines interact with Desvenlafaxine?

MediHelp also lists interactions of Desvenlafaxine with, for example, Isocarboxazid, Methylene blue, Phenelzine. The full list is on the Desvenlafaxine page.

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