Drug interactions
Devil's claw + Dipyridamole
Severity: Minor
Devil's claw and Dipyridamole: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Devil's claw has been reported to have antiplatelet activity and may add to the antiplatelet effect of dipyridamole. The clinical significance is uncertain and evidence is conflicting, but bleeding or bruising could theoretically increase.
What this interaction means in plain words
Devil's claw and Dipyridamole have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive inhibition of platelet function; the herbal effect is not well established.
What to do
Ask patients about herbal use and advise against routine use of devil's claw with dipyridamole. Monitor for bruising or bleeding if the combination is continued.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Dipyridamole
- Dipyridamole + Riociguat Contraindicated
- Adenosine + Dipyridamole Major
- Betrixaban + Dipyridamole Major
- Dabigatran + Dipyridamole Major
- Dipyridamole + Regadenoson Major
- Dipyridamole + Venetoclax Major
Frequently asked questions
Can I take Devil's claw with Dipyridamole?
MediHelp rates the interaction as minor. Devil's claw and Dipyridamole have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Devil's claw has been reported to have antiplatelet activity and may add to the antiplatelet effect of dipyridamole. The clinical significance is uncertain and evidence is conflicting, but bleeding or bruising could theoretically increase.
How serious is the interaction between Devil's claw and Dipyridamole?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Ask patients about herbal use and advise against routine use of devil's claw with dipyridamole. Monitor for bruising or bleeding if the combination is continued.
What other medicines interact with Dipyridamole?
MediHelp also lists interactions of Dipyridamole with, for example, Riociguat, Adenosine, Betrixaban. The full list is on the Dipyridamole page.
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